Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T73471
|
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| Former ID |
TTDR00510
|
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| Target Name |
Serine protease hepsin
|
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| Gene Name |
HPN
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| Synonyms |
HEPSIN; Transmembrane protease, serine 1; HPN
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| Target Type |
Research
|
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| Function |
Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2.
|
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| BioChemical Class |
Peptidase
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| UniProt ID | |||||
| EC Number |
EC 3.4.21.106
|
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| Sequence |
MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSAD
ARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCV DEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSL RYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYH GGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ YYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCE DSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL |
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| Pathways | |||||
| KEGG Pathway | Viral carcinogenesis | ||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | |||||
| References | |||||
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