Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T54931
|
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| Former ID |
TTDR00195
|
||||
| Target Name |
Nicotinic acetylcholine receptoralpha2 / alpha3
|
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| Target Type |
Research
|
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| Disease | Drug abuse [ICD9: 303-304; ICD10: F10-F19] | ||||
| UniProt ID | |||||
| Antagonist | 18-Methoxycoronaridine | Drug Info | [1] | ||
| Ibogaine | Drug Info | [1] | |||
| Laudanosine | Drug Info | [2] | |||
| Volatile anesthetics | Drug Info | [3] | |||
| Agonist | SIB-1533A | Drug Info | [4] | ||
| References | |||||
| REF 1 | Antagonism of alpha 3 beta 4 nicotinic receptors as a strategy to reduce opioid and stimulant self-administration. Eur J Pharmacol. 2002 Mar 1;438(1-2):99-105. | ||||
| REF 2 | Blockade and activation of the human neuronal nicotinic acetylcholine receptors by atracurium and laudanosine. Anesthesiology. 2001 Apr;94(4):643-51. | ||||
| REF 3 | The role of nicotinic acetylcholine receptors in the mechanisms of anesthesia. Brain Res Bull. 2002 Jan 15;57(2):133-50. | ||||
| REF 4 | Nicotine, brain nicotinic receptors, and neuropsychiatric disorders. Arch Med Res. 2000 Mar-Apr;31(2):131-44. | ||||
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