Target Information

Target General Infomation
Target ID
T28746
Former ID
TTDNS00552
Target Name
Kinase
Target Type
Clinical Trial
Disease Atherosclerosis; Psoriasis [ICD9:414.0, 440, 696; ICD10: I70, L40]
Drugs and Mode of Action
Drug(s) BMS-582949 Drug Info Phase 2 Atherosclerosis; Psoriasis [522211], [542780]
Modulator BMS-582949 Drug Info [532303]
References
Ref 522211ClinicalTrials.gov (NCT00605735) PoC in Rheumatoid Arthritis With Methotrexate. U.S. National Institutes of Health.
Ref 542780(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7838).
Ref 532303Synthesis and evaluation of carbamoylmethylene linked prodrugs of BMS-582949, a clinical p38alpha inhibitor. Bioorg Med Chem Lett. 2013 May 15;23(10):3028-33.

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