Target expression details
Target General Information | |||||
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Target ID | T82577 | ||||
Target Name | Angiotensin-converting enzyme | ||||
Synonyms | CD143 antigen; Dipeptidyl carboxypeptidase I; Kininase II; ACE | ||||
Target Type | Successful | ||||
Gene Name | ACE | ||||
Biochemical Class | Glycosylases | ||||
UniProt ID | ACE_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Depression | ||||
Example drug | Ceranapril | Discontinued in Phase 2 | [544627], [1572592] | ||
Tissue | Pre-frontal cortex | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.01 Z-score: -0.06 P-value: 2.62E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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