Target General Information
Target ID T74456
Target Name Type-1 angiotensin II receptor
Synonyms AT1; AT1AR; Angiotensin 1 receptor; Angiotensin II receptor 1; AGTR1
Target Type Successful
Gene Name AGTR1
Biochemical Class GPCR rhodopsin
UniProt ID AGTR1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Alzheimer's disease
Example drug RS-66252 Terminated [546339], [1572592]
Tissue Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 1.34E-02
Z-score: 0.07
P-value: 8.95E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 546339Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007561)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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