Target expression details
Target General Information | |||||
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Target ID | T69085 | ||||
Target Name | Transcription factor AP-1 | ||||
Synonyms | AP-1 transcription factor; AP1; Activator protein 1; Activator protein-1; C-jun proto-oncogene; P39; Proto-oncogene c-jun; V-jun avian sarcoma virus 17 oncogene homolog; JUN | ||||
Target Type | Discontinued | ||||
Gene Name | JUN | ||||
UniProt ID | JUN_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Rheumatoid arthritis | ||||
Example drug | T-5224 | Discontinued in Phase 2 | [547484], [1572592] | ||
Tissue | Synovial tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.92 Z-score: 1.87 P-value: 1.13E-03 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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