Target expression details
Target General Information | |||||
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Target ID | T68782 | ||||
Target Name | Prostaglandin D2 receptor | ||||
Synonyms | PGD receptor; Prostanoid DP receptor; PTGDR | ||||
Target Type | Clinical Trial | ||||
Gene Name | PTGDR | ||||
Biochemical Class | GPCR rhodopsin | ||||
UniProt ID | PD2R_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Asthma | ||||
Example drug | QAW-039 | Phase 3 | [525329], [1572592] | ||
Tissue | Nasal and bronchial airway | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.14 Z-score: -0.23 P-value: 7.32E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Disease | Atopic dermatitis | ||||
Example drug | TS-022 | Phase 2 | [522686], [1572592] | ||
Tissue | Skin | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.05 Z-score: -0.20 P-value: 7.32E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
Reference | |||||
Ref 522686 | ClinicalTrials.gov (NCT00914186) Study of TS-022 in Adult Patients With Atopic Dermatitis With Pruritus (POC). U.S. National Institutes of Health. |
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