Target expression details
Target General Information | |||||
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Target ID | T68163 | ||||
Target Name | Lyn tyrosine kinase | ||||
Synonyms | Lck/Yes-related novel protein tyrosine kinase; Tyrosine-protein kinase Lyn; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56Lyn; LYN | ||||
Target Type | Clinical Trial | ||||
Gene Name | LYN | ||||
Biochemical Class | Kinase | ||||
UniProt ID | LYN_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Prostate cancer | ||||
Example drug | Bafetinib | Phase 2 | [523198], [542828], [1572592] | ||
Tissue | Prostate | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.22 Z-score: -0.22 P-value: 1.70E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
Reference | |||||
Ref 542828 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7906). |
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