Target expression details
Target General Information | |||||
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Target ID | T60405 | ||||
Target Name | mRNA of RAF1 | ||||
Synonyms | C-RAF; CRaf; Raf kinase; Raf-1; RAF1 | ||||
Target Type | Clinical Trial | ||||
Gene Name | RAF1 | ||||
Biochemical Class | Target of antisense drug | ||||
UniProt ID | RAF1_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Melanoma | ||||
Example drug | MLN2480 | Phase 1 | [523603], [1572592] | ||
Tissue | Skin | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.03 Z-score: 0.05 P-value: 4.47E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Disease | Parkinson's disease | ||||
Example drug | SPN-803 | Phase 1 | [548872], [1572592] | ||
Tissue | Substantia nigra tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.49 Z-score: 2.78 P-value: 2.12E-04 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
Reference | |||||
Ref 548872 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029757) |
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