Target expression details
Target General Information | |||||
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Target ID | T58992 | ||||
Target Name | Opioid receptor delta-type | ||||
Synonyms | DOR-1; Delta opioid receptor; OPRD1 | ||||
Target Type | Successful | ||||
Gene Name | OPRD1 | ||||
Biochemical Class | GPCR rhodopsin | ||||
UniProt ID | OPRD_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Rheumatoid arthritis | ||||
Example drug | ADL-5859 | Phase 2 | [522241], [1572592] | ||
Tissue | Synovial tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.85 Z-score: -2.06 P-value: 1.85E-03 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Disease | Depression | ||||
Tissue | Pre-frontal cortex | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.03 Z-score: 0.23 P-value: 5.52E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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