Target expression details
Target General Information | |||||
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Target ID | T56923 | ||||
Target Name | C-X-C chemokine receptor type 2 | ||||
Synonyms | CDw128b; CXCR-2; GRO/MGSA receptor; IL-8 receptor type 2; IL-8R B; Interleukin-8 receptor B; CXCR2 | ||||
Target Type | Successful | ||||
Gene Name | CXCR2 | ||||
Biochemical Class | GPCR rhodopsin | ||||
UniProt ID | CXCR2_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Chronic obstructive pulmonary disease | ||||
Example drug | SB-656933 | Phase 2 | [543172], [550966], [1572592] | ||
Tissue | Lung tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.23 Z-score: -0.21 P-value: 8.82E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Disease | Chronic obstructive pulmonary disease | ||||
Example drug | SB-656933 | Phase 2 | [543172], [550966], [1572592] | ||
Tissue | Small airway epithelium | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.21 Z-score: 0.19 P-value: 1.34E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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