Target expression details
Target General Information | |||||
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Target ID | T49072 | ||||
Target Name | Urotensin II receptor | ||||
Synonyms | G protein coupled receptor 14; UR-II-R; Urotensin-II receptor GPR14; UTS2R | ||||
Target Type | Clinical Trial | ||||
Gene Name | UTS2R | ||||
Biochemical Class | GPCR rhodopsin | ||||
UniProt ID | UR2R_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Asthma | ||||
Example drug | GlaxoSmithKline | Phase 1 | [523601], [539371], [1572592] | ||
Tissue | Nasal and bronchial airway | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.25 Z-score: -0.57 P-value: 2.85E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Reference | |||||
Ref 539371 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2164). |
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