Target General Information
Target ID T42392
Target Name Glutamate receptor 2
Synonyms AMPAselective glutamate receptor 2; GluA2; GluR2; GluRB; GluRK2; Glutamate receptor ionotropic, AMPA 2; GRIA2
Target Type Clinical Trial
Gene Name GRIA2
Biochemical Class Glutamate-gated ion channel
UniProt ID GRIA2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Parkinson's disease
Example drug Paliroden Phase 2 [521794], [1572592]
Tissue Substantia nigra tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.08
Z-score: -0.14
P-value: 8.57E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 521794ClinicalTrials.gov (NCT00285025) Study of the Effect of SR57667B in Patients With Alzheimer's Disease. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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