Target General Information
Target ID	T38431
Target Name	Calgranulin B
Synonyms	Calprotectin L1H subunit; Leukocyte L1 complex heavy chain; MRP-14; MRP14; Migration inhibitory factor-related protein 14; Myeloid-related protein 14; P14; S100 calcium-binding protein A9; S100A9
Target Type	Clinical Trial
Gene Name	S100A9
Biochemical Class	S-100 family
UniProt ID	S10A9_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Prostate cancer
Example drug	Tasquinimod			Phase 3	[523240], [542970], [1572592]
Tissue	Prostate
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -1.43 Z-score: -0.90 P-value: 2.86E-03
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 542970	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8098).
Ref 523240	ClinicalTrials.gov (NCT01234311) A Study of Tasquinimod in Men With Metastatic Castrate Resistant Prostate Cancer. U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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