Target expression details
Target General Information | |||||
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Target ID | T33489 | ||||
Target Name | Steryl-sulfatase | ||||
Synonyms | ASC; Arylsulfatase C; Estrone sulfatase; Steroid sulfatase; Steryl-sulfate sulfohydrolase; STS | ||||
Target Type | Clinical Trial | ||||
Gene Name | STS | ||||
Biochemical Class | Sulfuric ester hydrolase | ||||
UniProt ID | STS_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Breast cancer | ||||
Example drug | COUMATE | Phase 2 | [531371], [1572592] | ||
Tissue | Breast tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.79 Z-score: -1.15 P-value: 1.80E-38 |
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Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section | Fold-change: -0.46 Z-score: -0.62 P-value: 1.56E-04 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
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Disease | Endometriosis | ||||
Example drug | PGL-2 | Phase 2 | [548563], [1572592] | ||
Tissue | Endometrium tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.29 Z-score: 0.67 P-value: 3.29E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Disease | Prostate cancer | ||||
Example drug | STX 64 | Phase 1 | [547916], [1572592] | ||
Tissue | Prostate | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.28 Z-score: -0.52 P-value: 4.91E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
Reference | |||||
Ref 547916 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020388) | ||||
Ref 548563 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026648) |
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