Target General Information
Target ID	T30687
Target Name	mRNA of GRL
Synonyms	mRNA of GR; mRNA of GRL; mRNA of NR3C1; mRNA of Nuclear receptor subfamily 3 group C member 1; NR3C1
Target Type	Clinical Trial
Gene Name	NR3C1
Biochemical Class	Zinc-finger
UniProt ID	GCR_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Type 2 diabetes
Example drug	A-348441			Phase 1	[1], [2]
Tissue	Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.54 Z-score: 1.67 P-value: 3.19E-02
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
REF 1	Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance. Metabolism. 2007 Mar;56(3):380-7.
REF 2	NCBI GEO: archive for functional genomics data sets--update.

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