Target expression details
Target General Information | |||||
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Target ID | T29754 | ||||
Target Name | MAPKAP kinase 5 | ||||
Synonyms | MAP kinaseactivated protein kinase 5; MAPKAP kinase 5; MAPKactivated protein kinase 5; MK5; PRAK; p38regulated/activated protein kinase; MAPKAPK5 | ||||
Target Type | Discontinued | ||||
Gene Name | MAPKAPK5 | ||||
Biochemical Class | Kinase | ||||
UniProt ID | MAPK5_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Rheumatoid arthritis | ||||
Example drug | GLPG-0259 | Discontinued in Phase 2 | [550825], [1572592] | ||
Tissue | Synovial tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.87 Z-score: 1.37 P-value: 5.33E-03 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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