Target General Information
Target ID T29754
Target Name MAPKAP kinase 5
Synonyms MAP kinaseactivated protein kinase 5; MAPKAP kinase 5; MAPKactivated protein kinase 5; MK5; PRAK; p38regulated/activated protein kinase; MAPKAPK5
Target Type Discontinued
Gene Name MAPKAPK5
Biochemical Class Kinase
UniProt ID MAPK5_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Rheumatoid arthritis
Example drug GLPG-0259 Discontinued in Phase 2 [550825], [1572592]
Tissue Synovial tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.87
Z-score: 1.37
P-value: 5.33E-03
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 550825Clinical pipeline report, company report or official report of Galapagos.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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