Target expression details
Target General Information | |||||
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Target ID | T25005 | ||||
Target Name | Tyrosine-protein kinase BTK | ||||
Synonyms | ATK; Agammaglobulinaemia tyrosine kinase; B cell progenitor kinase; BPK; Bruton's tyrosine kinase; BTK | ||||
Target Type | Successful | ||||
Gene Name | BTK | ||||
Biochemical Class | Kinase | ||||
UniProt ID | BTK_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Rheumatoid arthritis | ||||
Example drug | GDC-0834 | Terminated | [531450], [1572592] | ||
Tissue | Synovial tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.24 Z-score: 0.56 P-value: 3.54E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
Reference |
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