Target General Information
Target ID T19760
Target Name Mixed lineage kinase 1
Synonyms Mixed lineage kinase 1; MAP3K9
Target Type Clinical Trial
Gene Name MAP3K9
Biochemical Class Kinase
UniProt ID M3K9_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Asthma
Example drug CEP1347 Phase 2/3 [527447], [1572592]
Tissue Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.48
Z-score: 0.76
P-value: 9.49E-06
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 527447Targeting the JNK signaling pathway for stroke and Parkinson's diseases therapy. Curr Drug Targets CNS Neurol Disord. 2005 Feb;4(1):63-7.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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