Target expression details
Target General Information | |||||
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Target ID | T14558 | ||||
Target Name | Tryptase | ||||
Synonyms | Tryptase I; Tryptase alpha-1; Tryptase alpha/beta-1; TPSAB1 | ||||
Target Type | Successful | ||||
Gene Name | TPSAB1 | ||||
Biochemical Class | Peptidase | ||||
UniProt ID | TRYB1_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Asthma | ||||
Example drug | APC-366 | Discontinued in Phase 2 | [545523], [1572592] | ||
Tissue | Nasal and bronchial airway | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 1.07 Z-score: 0.89 P-value: 3.09E-07 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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