Target General Information
Target ID T14558
Target Name Tryptase
Synonyms Tryptase I; Tryptase alpha-1; Tryptase alpha/beta-1; TPSAB1
Target Type Successful
Gene Name TPSAB1
Biochemical Class Peptidase
UniProt ID TRYB1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Asthma
Example drug APC-366 Discontinued in Phase 2 [545523], [1572592]
Tissue Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 1.07
Z-score: 0.89
P-value: 3.09E-07
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 545523Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003595)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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