Target Validation Information | |||||
---|---|---|---|---|---|
Target ID | T22976 | ||||
Target Name | Deoxyribonucleoside phosphotransferase | ||||
Target Type | Research |
||||
Drug Potency against Target | 1-[6-(triphenylmethoxy)hexyl]thymine | Drug Info | IC50 = 17000 nM | [528583] | |
1-[5-(triphenylmethoxy)pentyl]thymine | Drug Info | IC50 = 15000 nM | [528583] | ||
1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | Drug Info | IC50 = 3300 nM | [528583] | ||
References | |||||
Ref 528583 | J Med Chem. 2006 Dec 28;49(26):7766-73.N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors. | ||||
Ref 528583 | J Med Chem. 2006 Dec 28;49(26):7766-73.N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors. | ||||
Ref 528583 | J Med Chem. 2006 Dec 28;49(26):7766-73.N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors. |
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