| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T46700 | ||||
| Target Name | mRNA of human cot oncogene | ||||
| Target Type | Research |
||||
| Drug Potency against Target | 8-chloro-quinoline-3-carbonitrile | Drug Info | IC50 = 12 nM | [529035] | |
| References | |||||
| Ref 529035 | J Biol Chem. 2007 Nov 16;282(46):33295-304. Epub 2007 Sep 11.Pharmacologic inhibition of tpl2 blocks inflammatory responses in primary human monocytes, synoviocytes, and blood. | ||||
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