| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T35194 | ||||
| Target Name | Dual specificity protein phosphatase 1 | ||||
| Target Type | Research |
||||
| Drug Potency against Target | ADOCIAQUINONE B | Drug Info | IC50 = 1100 nM | [529817] | |
| JUGLONE | Drug Info | IC50 = 13000 nM | [529817] | ||
| 4-ethoxynaphthalene-1,2-dione | Drug Info | IC50 = 820 nM | [529817] | ||
| References | |||||
| Ref 529817 | Bioorg Med Chem. 2009 Mar 15;17(6):2276-81. Epub 2008 Nov 8.Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. | ||||
| Ref 529817 | Bioorg Med Chem. 2009 Mar 15;17(6):2276-81. Epub 2008 Nov 8.Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. | ||||
| Ref 529817 | Bioorg Med Chem. 2009 Mar 15;17(6):2276-81. Epub 2008 Nov 8.Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. | ||||
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