Target Validation Information | |||||
---|---|---|---|---|---|
Target ID | T24334 | ||||
Target Name | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial | ||||
Target Type | Research |
||||
Drug Potency against Target | 1-[4-hydroxy-3-(tritylaminomethyl)butyl]uracil | Drug Info | Ki = 5700 nM | [528293] | |
1-[(Z)-4-trityloxy-2-butenyl]uracil | Drug Info | Ki = 5200 nM | [528293] | ||
1-[2-(trityloxy)ethoxymethyl]uracil | Drug Info | Ki = 17000 nM | [528293] | ||
1-(3-tritylaminopropyl)uracil | Drug Info | Ki = 1400 nM | [528293] | ||
References | |||||
Ref 528293 | J Med Chem. 2006 Jul 13;49(14):4183-95.Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. | ||||
Ref 528293 | J Med Chem. 2006 Jul 13;49(14):4183-95.Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. | ||||
Ref 528293 | J Med Chem. 2006 Jul 13;49(14):4183-95.Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. | ||||
Ref 528293 | J Med Chem. 2006 Jul 13;49(14):4183-95.Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. |
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