| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T82702 | ||||
| Target Name | Pregnane X receptor | ||||
| Target Type | Research |
||||
| Drug Potency against Target | WAY-214950 | Drug Info | IC50 = 2160 nM | [529781] | |
| WAY-252623 | Drug Info | IC50 = 1770 nM | [529781] | ||
| References | |||||
| Ref 529781 | J Med Chem. 2008 Nov 27;51(22):7161-8.Indazole-based liver X receptor (LXR) modulators with maintained atherosclerotic lesion reduction activity but diminished stimulation of hepatic triglyceride synthesis. | ||||
| Ref 529781 | J Med Chem. 2008 Nov 27;51(22):7161-8.Indazole-based liver X receptor (LXR) modulators with maintained atherosclerotic lesion reduction activity but diminished stimulation of hepatic triglyceride synthesis. | ||||
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