| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T16156 | ||||
| Target Name | Thrombopoietin Receptor | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | E5501 | Drug Info | pKi = 7.76 | [552671] | |
| Totrombopag | Drug Info | IC50 = 170 nM | [552881] | ||
| References | |||||
| Ref 552671 | Agonists and antagonists targeting the different alpha2-adrenoceptor subtypes. Curr Top Med Chem. 2007;7(2):163-86. | ||||
| Ref 552881 | Recent advances in the development of multi-kinase inhibitors. Mini Rev Med Chem. 2008 Nov;8(13):1312-27. | ||||
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