| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T38301 | ||||
| Target Name | Ribonucleoside-diphosphatereductase subunit M2 | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | Motexafin gadolinium | Drug Info | IC50 = 6 microM | [536181] | |
| References | |||||
| Ref 536181 | Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase. J Biol Chem. 2006 Apr 21;281(16):10691-7. Epub 2006 Feb 14. | ||||
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