Target Validation Information
Target ID T70680
Target Name Organic anion transporter 1
Target Type
Successful
Drug Potency against Target HEPTANOATE Drug Info Ki = 16700 nM [528881]
ADIPATE Drug Info Ki = 410 nM [528881]
3R14S-OCHRATOXIN A Drug Info Ki = 6200 nM [528881]
FLUORESCEIN Drug Info Ki = 3000 nM [528881]
GLUTARATE Drug Info Ki = 6700 nM [528881]
AMINOHIPPURIC ACID Drug Info Ki = 9400 nM [528881]
References
Ref 528881J Biol Chem. 2007 Aug 17;282(33):23841-53. Epub 2007 Jun 5.Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
Ref 528881J Biol Chem. 2007 Aug 17;282(33):23841-53. Epub 2007 Jun 5.Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
Ref 528881J Biol Chem. 2007 Aug 17;282(33):23841-53. Epub 2007 Jun 5.Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
Ref 528881J Biol Chem. 2007 Aug 17;282(33):23841-53. Epub 2007 Jun 5.Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
Ref 528881J Biol Chem. 2007 Aug 17;282(33):23841-53. Epub 2007 Jun 5.Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
Ref 528881J Biol Chem. 2007 Aug 17;282(33):23841-53. Epub 2007 Jun 5.Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.

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