| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T34287 | ||||
| Target Name | Mannose-6-phosphate isomerase | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | NSC-66209 | Drug Info | IC50 = 3550 nM | [531262] | |
| GNF-PF-5134 | Drug Info | IC50 = 13733 nM | [531262] | ||
| GNF-PF-2272 | Drug Info | IC50 = 6088 nM | [531262] | ||
| References | |||||
| Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
| Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
| Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
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