| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T93440 | ||||
| Target Name | Interleukin-6 receptor | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | Tocilizumab | Drug Info | Kd = 2.54+/-0.12 nM | [552541] | |
| References | |||||
| Ref 552541 | Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family. Int Immunopharmacol. 2005 Nov;5(12):1731-40. | ||||
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