Drug General Information
Drug ID	D06GSS
Drug Name	Calcifediol
Synonyms	Calderol
Drug Type	Small molecular drug
Indication	Vitamin D deficiency [ICD9: 268; ICD10:E55]		Approved	[551871]
Company	Organon Usa Inc
Structure		Download 2D MOL 3D MOL
Formula	C27H44O2
PubChem Compound ID	166583
Target and Pathway
Target(s)	Vitamin D receptor	Target Info	Modulator	[556264]
KEGG Pathway	Endocrine and other factor-regulated calcium reabsorption
	Mineral absorption
	Tuberculosis
NetPath Pathway	IL4 Signaling Pathway
PANTHER Pathway	Vitamin D metabolism and pathway
Pathway Interaction Database	Regulation of nuclear SMAD2/3 signaling
	Direct p53 effectors
	RXR and RAR heterodimerization with other nuclear receptor
	Retinoic acid receptors-mediated signaling
	Validated transcriptional targets of deltaNp63 isoforms
	Validated transcriptional targets of TAp63 isoforms
Reactome	Nuclear Receptor transcription pathway
WikiPathways	Ovarian Infertility Genes
	Nuclear Receptors in Lipid Metabolism and Toxicity
	Nuclear Receptors Meta-Pathway
	Vitamin D Receptor Pathway
	Drug Induction of Bile Acid Pathway
	Nuclear Receptors
	Vitamin D Metabolism
References
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 556264	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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