Drug Information

Drug General Information
Drug ID
D0W7FC
Former ID
DIB007118
Drug Name
MLN-2704
Synonyms
MLN-5591DM1; MLN-591DM1; ATG-J591: DM1
Drug Type
Antibody
Indication Prostate cancer [ICD9: 185; ICD10:C61] Phase 1/2 [521575]
Company
Millennium Pharmaceuticals
Target and Pathway
Target(s) Glutamate carboxypeptidase II Target Info [529391]
KEGG Pathway Alanine, aspartate and glutamate metabolism
Metabolic pathways
Vitamin digestion and absorption
NetPath Pathway TCR Signaling Pathway
TNFalpha Signaling Pathway
Reactome Amino acid synthesis and interconversion (transamination)
WikiPathways One Carbon Metabolism
References
Ref 521575ClinicalTrials.gov (NCT00070837) MLN2704 in Subjects With Metastatic Androgen-Independent Prostate Cancer. U.S. National Institutes of Health.
Ref 529391Phase I trial of the prostate-specific membrane antigen-directed immunoconjugate MLN2704 in patients with progressive metastatic castration-resistant prostate cancer. J Clin Oncol. 2008 May 1;26(13):2147-54.

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