Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W8VC
|
||||
| Former ID |
DIB012461
|
||||
| Drug Name |
PA-1637
|
||||
| Synonyms |
Copper chelating agents (neurodegenerative disease), Palumed
|
||||
| Indication | Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10:I21, I22, R52, R52.1-R52.2, R60.9, G89] | Investigative | [543619] | ||
| Company |
Palumed SA
|
||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Modulator | [543619] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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