Drug Information
Drug General Information | |||||
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Drug ID |
D0UJ0D
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Former ID |
DNCL003634
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Drug Name |
ISIS-FGFR4Rx
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Indication | Obesity [ICD9: 278; ICD10:E66] | Phase 2 | [525236] | ||
Company |
ISIS pharmaceuticals
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Target and Pathway | |||||
Target(s) | FGF-4 receptor | Target Info | Modulator | [543498] | |
PANTHER Pathway | FGF signaling pathway | ||||
Pathway Interaction Database | FGF signaling pathway | ||||
Reactome | PI3K Cascade | ||||
PIP3 activates AKT signaling | |||||
FGFR4 ligand binding and activation | |||||
Constitutive Signaling by Aberrant PI3K in Cancer | |||||
Phospholipase C-mediated cascade | |||||
FRS-mediated FGFR4 signaling | |||||
SHC-mediated cascade:FGFR4 | |||||
PI-3K cascade:FGFR4 | |||||
Negative regulation of FGFR4 signaling | |||||
RAF/MAP kinase cascade | |||||
References |
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