Drug General Information
Drug ID
D06NPB
Former ID
DND000033
Drug Name
GLPG-0259
Synonyms
G-13919, GT-146, GT-1498, GT-1704, GT-314, GT-416, GT-514, GT-562
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Discontinued in Phase 2 [550825]
Company
Johnson&Johnson
Structure
Download
2D MOL

3D MOL

Target and Pathway
Target(s) MAPKAPK5 Target Info Inhibitor [543554]
Pathway Interaction Database Signaling mediated by p38-alpha and p38-beta
Reactome Oxidative Stress Induced Senescence
MAPK6/MAPK4 signaling
WikiPathways p38 MAPK Signaling Pathway
MAPK Signaling Pathway
References
Ref 550825Clinical pipeline report, company report or official report of Galapagos.
Ref 543554(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2096).

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