Drug Information

Drug General Information
Drug ID
D0F1WD
Former ID
DIB000460
Drug Name
C-10068
Synonyms
C-10068; Deuterated sigma-1 agonists (epilepsy/brain injury/neuropathic pain); Deuterated sigma-1 agonists (epilepsy/brain injury/neuropathic pain), CoNCERT/Walter Reed Army Institute
Indication Brain injury [ICD10:S09.90] Investigative [526642], [532713]
Company
CoNCERT Pharmaceuticals Inc
Target and Pathway
Target(s) Sigma(1)-type opioid receptor Target Info Agonist [526642], [532713]
WikiPathways miR-targeted genes in squamous cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 526642Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6.
Ref 532713Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82.
Ref 526642Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6.
Ref 532713Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82.

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