TTD | Drug: D0YW6P

Drug General Information
Drug ID	D0YW6P
Former ID	DIB014762
Drug Name	RU-101
Synonyms	RU-10; Recombinant human serum albumin (ocular, dry eye), R-Tech Ueno
Indication	Xerophthalmia [ICD10:E50.6-E50.7]		Phase 1/2	[524273]
Company	R-tech ueno
Target and Pathway
Target(s)	Serum albumin	Target Info	Modulator	[544031]
Pathway Interaction Database	FOXA2 and FOXA3 transcription factor networks
Reactome	Platelet degranulation
	Recycling of bile acids and salts
	HDL-mediated lipid transport
	Scavenging of heme from plasma
WikiPathways	Human Complement System
	Binding and Uptake of Ligands by Scavenger Receptors
	Lipid digestion, mobilization, and transport
	Transport of vitamins, nucleosides, and related molecules
	Bile acid and bile salt metabolism
	Folate Metabolism
	Vitamin B12 Metabolism
	Selenium Micronutrient Network
References
Ref 524273	ClinicalTrials.gov (NCT01843894) A Phase 1/2, RU-101 Ophthalmic Solution in Patients With Severe Dry Eye. U.S. National Institutes of Health.
Ref 544031	Albumin as a tear supplement in the treatment of severe dry eye. Br J Ophthalmol. 2003 October; 87(10): 1279-1283.

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Drug Information