Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0CA3J
|
||||
| Former ID |
DNCL001786
|
||||
| Drug Name |
GSK568859
|
||||
| Indication | Atherosclerosis [ICD9: 414.0, 440; ICD10:I70] | Discontinued in Phase 1 | [1] | ||
| Company |
GlaxoSmithKline
|
||||
| Target and Pathway | |||||
| Target(s) | Lipoprotein-associated phospholipase A2 | Target Info | Modulator | [2] | |
| KEGG Pathway | Ether lipid metabolism | ||||
| Metabolic pathways | |||||
| Biosynthesis of antibiotics | |||||
| Pathway Interaction Database | Lissencephaly gene (LIS1) in neuronal migration and development | ||||
| WikiPathways | IL1 and megakaryotyces in obesity | ||||
| Synthesis, Secretion, and Deacylation of Ghrelin | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025982) | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1432). | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.