Drug Information
Drug General Information | |||||
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Drug ID |
D0Z4EI
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Former ID |
DIB010980
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Drug Name |
Mifepristone
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Synonyms |
Mifedren; HRA-052015; Mifepristone (Cushing's disease); ACTH modulator (Cushing's disease), HRA; Adrenocorticotropic hormone modulator (Cushing's disease), HRA Pharma; Mifepristone (Cushing's disease), HRA pharma
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Drug Type |
Small molecular drug
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Company |
HRA Pharma
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Structure |
Download2D MOL |
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Formula |
C29H35NO2
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InChI |
InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1
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InChIKey |
VKHAHZOOUSRJNA-GCNJZUOMSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
9854, 610895, 827617, 7847651, 7885329, 7979988, 8184037, 10321543, 11466327, 11467447, 11486193, 11533034, 12013919, 12146248, 14758749, 14905326, 17405362, 24278572, 26752199, 26759172, 34719152, 46386955, 46505795, 46518693, 47573358, 47720589, 47795017, 47795018, 48018884, 48318385, 48393908, 48416281, 49698423, 49835339, 49965772, 50124354, 50576278, 53777907, 53788556, 56312231, 56313355, 56313657, 56313765, 56352854, 56424093, 57313727, 85752924, 85789352, 90341299, 92125204
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Target and Pathway | |||||
Target(s) | Glucocorticoid receptor | Target Info | Modulator | [528847] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
NetPath Pathway | IL2 Signaling Pathway | ||||
TCR Signaling Pathway | |||||
References | |||||
Ref 525064 | ClinicalTrials.gov (NCT02342002) Mifepristone and Misoprostol Versus Misoprostol Alone for Missed Abortion: A Randomized-controlled Trial. U.S. National Institutes of Health. | ||||
Ref 539846 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2805). | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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