Drug Information

Drug General Information
Drug ID
D0N7FD
Former ID
DIB003955
Drug Name
Multi-epitope tyrosinase/gp100 vaccine
Synonyms
Melanoma vaccine, Memorial Sloan-Kettering; Multi-epitope tyrosinase/gp100 vaccine (melanoma); Multi-epitope tyrosinase/gp100 vaccine (melanoma), Memorial Sloan-Kettering
Drug Type
Vaccine
Indication Melanoma [ICD9: 172; ICD10:C43] Phase 2 [521451]
Company
Memorial Sloan-Kettering Cancer Center
Target and Pathway
Target(s) Melanocytes lineage-specific antigen GP100 Target Info [521451]
Tyrosine oxidase Target Info [521451]
BioCyc Pathway (S)-reticuline biosynthesis
Eumelanin biosynthesis
L-dopachrome biosynthesis
KEGG Pathway Tyrosine metabolism
Riboflavin metabolism
Metabolic pathways
Melanogenesis
PathWhiz Pathway Riboflavin Metabolism
Tyrosine Metabolism
WikiPathways Dopamine metabolism
References
Ref 521451ClinicalTrials.gov (NCT00003362) Vaccine Therapy Plus Immune Adjuvants in Treating Patients With Advanced Melanoma. U.S. National Institutes of Health.
Ref 521451ClinicalTrials.gov (NCT00003362) Vaccine Therapy Plus Immune Adjuvants in Treating Patients With Advanced Melanoma. U.S. National Institutes of Health.

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