Drug Information

Drug General Information
Drug ID
D0T9MQ
Former ID
DIB001538
Drug Name
KN-203
Synonyms
Mu-opioid recceptor agonist (urinary incontinence), Grunenthal/KeyNeurotek
Indication Urinary incontinence [ICD9: 788.3; ICD10:N39.3, N39.4, R32] Discontinued in Phase 1 [548523]
Company
Grunenthal GmbH
Target and Pathway
Target(s) Mu-type opioid receptor Target Info Agonist [548524]
KEGG Pathway Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addiction
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Pathway Interaction Database IL4-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways TCR Signaling Pathway
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
Opioid Signalling
GPCR ligand binding
GPCR downstream signaling
References
Ref 548523Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026307)
Ref 548524Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026307)

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