Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0HD8X
|
||||
| Former ID |
DNCL002723
|
||||
| Drug Name |
ISF35
|
||||
| Indication | Chronic lymphocytic leukaemia; Mantle cell lymphoma; Small lymphocytic lymphoma [ICD9: 200.0, 200.4, 202.0, 202.8, 204.0, 204.1V10.60, 208.9; ICD10:C91, C81-C86, C82, C83.3, C85.7, C91-C95, C91.0, C91.1] | Phase 2 | [522732] | ||
| Company |
Memgen
|
||||
| Target and Pathway | |||||
| Target(s) | Tumor necrosis factor ligand superfamily member 5 | Target Info | Binder | [533021] | |
| KEGG Pathway | Cytokine-cytokine receptor interaction | ||||
| NF-kappa B signaling pathway | |||||
| Cell adhesion molecules (CAMs) | |||||
| T cell receptor signaling pathway | |||||
| Intestinal immune network for IgA production | |||||
| Malaria | |||||
| Toxoplasmosis | |||||
| Asthma | |||||
| Autoimmune thyroid disease | |||||
| Systemic lupus erythematosus | |||||
| Allograft rejection | |||||
| Primary immunodeficiency | |||||
| Viral myocarditis | |||||
| References | |||||
| Ref 522732 | ClinicalTrials.gov (NCT00942409) Study of Repeat Intranodal Injection of Memgen's Cancer Vaccine, Ad-ISF35, in Subjects With Non-Hodgkin's Lymphoma (Follicular, Diffuse Large Cell, Mantle Cell, and Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia. U.S. National Institutes of Health. | ||||
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