Drug General Information
Drug ID
D08JYV
Former ID
DIB016269
Drug Name
PSMA subunit vaccine
Synonyms
Recombinant soluble PSMA vaccine; RsPSMA vaccine; PSMA subunit vaccine (prostate cancer); PSMA recombinant soluble protein vaccine, CYTOGEN/Progenics; PSMA rs protein vaccine, CYTOGEN/Progenics; PSMA protein vaccine (prostate cancer), Progenics/CYTOGEN; PSMA purified protein vaccine (prostate cancer), Progenics/CYTOGEN; PSMA subunit vaccine (prostate cancer), Progenics/CYTOGEN; PSMA-based therapeutics, CYTOGEN/Progenics
Drug Type
Vaccine
Indication Prostate cancer [ICD9: 185; ICD10:C61] Phase 1 [550234]
Company
Alphavax
Target and Pathway
Target(s) Glutamate carboxypeptidase II Target Info [543445]
KEGG Pathway Alanine, aspartate and glutamate metabolism
Metabolic pathways
Vitamin digestion and absorption
NetPath Pathway TCR Signaling Pathway
TNFalpha Signaling Pathway
Reactome Amino acid synthesis and interconversion (transamination)
WikiPathways One Carbon Metabolism
References
Ref 550234Clinical pipeline report, company report or official report of Alphavax.
Ref 543445(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1606).

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