Drug Information

Drug General Information
Drug ID
D0FJ9W
Former ID
DIB016717
Drug Name
KB-004
Synonyms
Anti-EphA3 tyrosine kinase receptor monoclonal antibody (Humaneered, iv, cancer), KaloBios
Drug Type
Antibody
Indication Hematological malignancies [ICD9: 200-209; ICD10:C81-C86] Phase 1/2 [523188]
Company
KaloBios Pharmaceuticals Inc
Target and Pathway
Target(s) Epha3 tyrosine kinase receptor Target Info [549957]
KEGG Pathway Axon guidance
Pathway Interaction Database EphrinA-EPHA pathway
EPHA forward signaling
Reactome EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells
WikiPathways NRF2 pathway
References
Ref 523188ClinicalTrials.gov (NCT01211691) Study of KB004 in Subjects With Hematologic Malignancies (Myelodysplastic Syndrome, MDS, Myelofibrosis, MF). U.S. National Institutes of Health.
Ref 549957Clinical pipeline report, company report or official report of Kalobios.

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