Drug General Information
Drug ID
D0A4UW
Former ID
DIB011513
Drug Name
BAY-86-7548
Synonyms
Bombesin-68Ga-labeled tracer (PET/CT cancer imaging), Bayer
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 1 [523178]
Company
Bayer AG
Target and Pathway
Target(s) Bombesin receptor Target Info Enhancer [532299]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
References
Ref 523178ClinicalTrials.gov (NCT01205321) PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and Healthy Volunteers. U.S. National Institutes of Health.
Ref 532299Plasma pharmacokinetics, whole-body distribution, metabolism, and radiation dosimetry of 68Ga bombesin antagonist BAY 86-7548 in healthy men. J Nucl Med. 2013 Jun;54(6):867-72.

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