Drug Information

Drug General Information
Drug ID
D0L8OP
Former ID
DIB015081
Drug Name
AVP-21D9
Synonyms
Thravixa; AVP-1C6; AVP-22G12; AVP-8C1; Anthrax antibody, AVANIR; Anthrax toxin Mab, Xenerex; Protective antigen-targeting human monoclonal antibodies (intravenous, anthrax), AVANIR; Protective antigen-targeting human monoclonal antibodies (intravenous, anthrax), Emergent
Drug Type
Antibody
Indication Bacillus anthracis infection [ICD10:A22] Phase 1 [523172]
Company
Emergent biosolutions
Target and Pathway
Target(s) Protective antigen Target Info [544420]
Pathway Interaction Database Cellular roles of Anthrax toxin
Reactome Uptake and function of anthrax toxins
References
Ref 523172ClinicalTrials.gov (NCT01202695) Safety and Pharmacokinetics Study of Human Monoclonal Antibody (AVP-21D9). U.S. National Institutes of Health.
Ref 544420Efficacy and Safety of AVP-21D9, an Anthrax Monoclonal Antibody, in Animal Models and Humans. Antimicrob Agents Chemother. 2014 July; 58(7): 3618-3625.

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