Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0T6ES
|
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| Former ID |
DIB012844
|
||||
| Drug Name |
SSR-125329A
|
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| Synonyms |
SR-125329; N-[3-[4-(2-Adamantyl)-3,5-dichlorophenyl]-2(Z)-propenyl]-N-cyclohexyl-N-ethylamine
|
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| Indication | Immuno-modulator [ICD9: 135, 691.8, 692.9, 710-719, 714; ICD10:D86, L20, L20-L30, M00-M25, M05-M06] | Phase 1 | [526469] | ||
| Target and Pathway | |||||
| Target(s) | Sigma(1)-type opioid receptor | Target Info | Binder | [526469], [526642], [532713] | |
| References | |||||
| Ref 526469 | SSR125329A, a high affinity sigma receptor ligand with potent anti-inflammatory properties. Eur J Pharmacol. 2002 Dec 5;456(1-3):123-31. | ||||
| Ref 526642 | Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6. | ||||
| Ref 532713 | Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82. | ||||
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