Drug Information

Drug General Information
Drug ID
D0I0SY
Former ID
DIB001164
Drug Name
MEDI-542
Synonyms
Ephrin a4-targeting monoclonal antibody (cancer), MedImmune
Drug Type
Antibody
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Terminated [548047]
Company
Medlmmune LLC
Target and Pathway
Target(s) Epha4 tyrosine kinase receptor Target Info [551569]
KEGG Pathway Axon guidance
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database EphrinA-EPHA pathway
EPHA forward signaling
Reactome EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells
WikiPathways Gene regulatory network modelling somitogenesis
Spinal Cord Injury
References
Ref 548047Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021498)
Ref 551569Product Pipeline Review of MedImmune, LLC in 2012.

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