Drug General Information
Drug ID	D0X2AT
Former ID	DIB012018
Drug Name	Rhopressa
Indication	Glaucoma [ICD9: 365; ICD10:H40-H42]		Phase 2	[533091]
Company	Aerie pharmaceuticals
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Sodium-dependent noradrenaline transporter	Target Info	Modulator	[533091]
	Rho associated protein kinase	Target Info	Modulator	[533091]
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
Reactome	Na+/Cl- dependent neurotransmitter transporters
WikiPathways	Monoamine Transport
	NRF2 pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 533091	Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.
Ref 533091	Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.

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