TTD | Drug: D0K0IW

Drug General Information
Drug ID	D0K0IW
Former ID	DCL000093
Drug Name	CRA-028129
Indication	Psoriatic disorder [ICD9: 696; ICD10:L40]		Terminated	[548110]
Company	Celera Genomics
Formula	C24H28N2O5
Target and Pathway
Target(s)	Cathepsin S	Target Info	Inhibitor	[551432]
KEGG Pathway	Lysosome
	Phagosome
	Antigen processing and presentation
	Tuberculosis
NetPath Pathway	Leptin Signaling Pathway
NetPath Pathway	IL2 Signaling Pathway
Reactome	Endosomal/Vacuolar pathway
	Degradation of the extracellular matrix
	Trafficking and processing of endosomal TLR
	Assembly of collagen fibrils and other multimeric structures
	MHC class II antigen presentation
WikiPathways	Class I MHC mediated antigen processing & presentation
WikiPathways	Trafficking and processing of endosomal TLR
References
Ref 548110	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022029)
Ref 551432	Phase I clinical trial for cathepsin S inhibitor for psoriasis begins. Celera Genomics. 2005.

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Drug Information